Systematic condition-dependent annotation of metabolic genes
نویسندگان
چکیده
منابع مشابه
Systematic condition-dependent annotation of metabolic genes.
The task of deriving a functional annotation for genes is complex as their involvement in various processes depends on multiple factors such as environmental conditions and genetic backup mechanisms. This study employs a large-scale model of the metabolism of Saccharomyces cerevisiae to investigate the function of yeast genes and derive a condition-dependent annotation (CDA) for their involveme...
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The immune and the detoxication systems of animals are characterized by allelic polymorphisms, which underlie individual differences in ability to combat assaults from pathogens and toxic compounds. Previous studies have shown that females may improve offspring survival by selecting mates on the basis of sexual ornaments and signals that honestly reveal health. In many cases the expression of t...
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The concept of the gene plays a fundamental role both in the interpretation and in the organization and storage of molecular biology data. Genes are treated as if they were unambiguously characterized physical entities with clearly defined measurable properties. The ubiquitous usage of genes in current bio-databases reinforces this perception. A closer look at the data models and the ongoing di...
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UNLABELLED AMIGene (Annotation of MIcrobial Genes) is an application for automatically identifying the most likely coding sequences (CDSs) in a large contig or a complete bacterial genome sequence. The first step in AMIGene is dedicated to the construction of Markov models that fit the input genomic data (i.e. the gene model), followed by the combination of well-known gene-finding methods and a...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2007
ISSN: 1088-9051
DOI: 10.1101/gr.6678707